Expertise
Our Services
This is a small overview of the services that we offer and the expertise that we have. Can’t find your research topic?
Single Cell Data Analysis
Single cell data analysis gives insight into the transcriptomic state on a single cell level allowing to decipher cellular subpopulations within a tissue or organism. The bioinformatic analysis can include sequencing of single cells as well as nuclei and methods such as CITE-seq and more.
Analysis of RNA-Sequencing Data
The bioinformatic analysis of bulk RNA-Sequencing data gives insight into the transcriptome of a tissue or organism to study gene and pathway expression levels. Next to mRNA, we also offer the analysis of small RNAs such as microRNAs.
Epigenomics Data Analysis
We analyse NGS-data of the epigenomic state of a cell to help associate identified genomic sites to phenotypic attributes. This may include binding sites of transcription factors, segments of open chromatin, methylated CpG islands or histone locations as well as modifications.
Spectral Flow Cytometry Analysis
We have experience with cytometry technolgies such as Cytek® Aurora allowing characterization of immune cell populations, cancer research, drug development, and any application where researchers need to simultaneously measure many cellular markers to understand complex biological systems. It's especially useful when studying rare cell populations that might be missed with fewer parameters or when trying to understand the full spectrum of cellular diversity within tissues.
Proteomic - Olink Data Analysis
High throughput protemics, i.e.quantifying hundrets of proteins at the same time has been has been almost impossible so far. But recently, Olink came up a new Explore up to 5,400 proteins with high specificity, transparent data, and the flexibility to answer any research question. The Olink panels for targeted protein biomarker discovery enable faster, better-informed decisions in human protein biomarker research by providing high-multiplex immunoassays benefits. However the data anysis is rather complex and requires experience - which we have!
Custom Software Solutions
We offer tailored bioinformatic pipelines (such as Nextflow or Snakemake) to fit your data analysis needs. Just contact us to discuss your specific research questions.
Proteomics - Mass spectrometry
Another approach to quantify proteins is mass spectrometry, allowing a deep, unbiased, and scalable proteomic analysis of complex biofluids like plasma. Recently Seer released a nanoparticle based assays that allows to quantify thousands of proteins. This is an alternative unbiased approach compared to targeted approaches such as Olink. It comes with its own quirks. But we have you covered!
Designing and building database-warehouse
Connecting the dots. Analysing data is only half the story, saving and structuring is essential for gaining actionable insights. This is best achieved by building in house databases which need to be heavily costumized to the companies use cases. We can help to build those. This also paves the way for AI integration! Think having a chatbot that can talk to your data and connecting the dots, we can help building it.
Cloud based computing
We offer to store and analyse your data on Amazon AWS making the most of what the cloud has to offer.
What we don't do
Since we specialize in bioinformatics in general and sequence analysis, however to maintain our focus we however won't do:
- Image analysis
- GUI development
- Network analysis